Complement C3a
Test Code: LAB9327
CPT Code: 86160
Interface Code
C3A
Synonym
C3A DESARG FRAGMENT, C3A COMPLEMENT PROTEIN, C3 ANAPHYLATOXIN, FC3AL, Complement C3a des-Arginine
Specimen Type
Plasma (EDTA) with Futhan, frozen
Specimen Container
Lavender-top (EDTA) tube
Specimen Handling
Collect EDTA whole blood sample into a chilled lavender-top tube. Immediately add Futhan preservative as directed in the Futhan collection kit (LabCorp N° 78946). Recap lavender tube and invert several times to mix well. Centrifuge the whole blood specimen to separate the plasma. Transfer the plasma into the plastic screw-cap tube that is included in the collection kit. The specimen must be submitted in this transfer tube, which is labeled with the words "Futhan Added." Freeze immediately and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Volume
1 mL
Minimum Volume
0.5 mL (Note: This volume does not allow for repeat testing.)
Temperature
Freeze
Unacceptable Conditions
Any tube other than a tube labeled with the "Futhan Added" sticker will be rejected; nonfrozen specimen received; non-EDTA plasma sample received
Methodology
Radioimmunoassay (RIA)
Additional Information
Futhan preservative must be added to samples immediately after collection. Collection kits containing this preservative are available as LabCorp N° 78946. Results for this test are for research purposes only by the assay's manufacturer. The performance characteristics of this product have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.
Elevation of C3a levels is not predictive of any specific disease. Persons with lupus erythematosus, obstructive pulmonary disease, asthma, age-related macular degeneration, and pancreatic and autoimmune conditions may have inflammation with elevated C3a levels.
Samples that are not properly collected and stored will produce erroneously elevated results due to in vitro activation.12 Blood must be drawn directly into tubes containing EDTA at a final concentration of at least 10 mM with the addition of nafamostat mesilate (Futhan, FUT-1750) to further reduce in vitro complement activation. For more information please refer to https://www.labcorp.com/test-menu/23011/complement-csub3-suba.
Elevation of C3a levels is not predictive of any specific disease. Persons with lupus erythematosus, obstructive pulmonary disease, asthma, age-related macular degeneration, and pancreatic and autoimmune conditions may have inflammation with elevated C3a levels.
Samples that are not properly collected and stored will produce erroneously elevated results due to in vitro activation.12 Blood must be drawn directly into tubes containing EDTA at a final concentration of at least 10 mM with the addition of nafamostat mesilate (Futhan, FUT-1750) to further reduce in vitro complement activation. For more information please refer to https://www.labcorp.com/test-menu/23011/complement-csub3-suba.
Stability
Room Temperature: 24 hours
Refrigerated: 6 hours
Frozen: 14 days
Freeze/thaw cycles: Stable x1
Refrigerated: 6 hours
Frozen: 14 days
Freeze/thaw cycles: Stable x1
Reference Range Information
Reference values are dependent upon methodology/instrumentation, check final report for current reference values
Turn Around Time
4-7 days
Performing Site
LabCorp
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