LEAD, URINE
Test Code: LAB404
CPT Code: 82570 001 83655 001
Interface Code
ULEAD
Synonym
HEAVY METAL, PB, 24 HR, RANDON, LEAD, 007633
Specimen Type
Urine (random or 24-hour)
Specimen Container
Plastic urine container, no preservative
Specimen Handling
Sampling time is not critical for industrial exposure monitoring. Metals with timing “not critical” have very long elimination half-lives and accumulate in the body over years, some for a lifetime. After a couple of weeks of exposure, specimens can be collected at any time.
Optional protocol: If the specimen is a 24-hour collection, instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Collect without preservatives. Mix well. Sampling time is not critical for industrial monitoring.
Optional protocol: If the specimen is a 24-hour collection, instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Collect without preservatives. Mix well. Sampling time is not critical for industrial monitoring.
Volume
5 mL
Minimum Volume
2.5 mL
Temperature
Room Temperature
Methodology
Inductively coupled plasma/mass spectrometry (ICP/MS)
Additional Information
Request form must state total volume collected in 24-hour, if applicable. Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing. This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Stability
Room Temperature: 14 days
Refrigerated: 14 days
Frozen: 14 days
Freeze/thaw cycles: Stable x3
Refrigerated: 14 days
Frozen: 14 days
Freeze/thaw cycles: Stable x3
Reference Range Information
• Environmental exposure: <50 μg/L, <80 μg/24 hours
• Occupation exposure: BEI® (sampling time is not critical): 150 μg/g creatinine;1 chelation therapy: <600 μg/24 hours (after 1 g EDTA I.V. or 2 g DMSA P.O.)
• Occupation exposure: BEI® (sampling time is not critical): 150 μg/g creatinine;1 chelation therapy: <600 μg/24 hours (after 1 g EDTA I.V. or 2 g DMSA P.O.)
Turn Around Time
3-4 days
Performing Site
LabCorp Laboratory
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